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While more convenient and non-invasive, its safety and effectiveness are still under investigation and not established

doi: 10.1016/s1875-5364(18)30110-9 61 LuY.SunJ.PetrovaK.YangX.GreenhawJ.SalminenW

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Dosage and administration Typical protocols in the literature and clinical practice use subcutaneous injection , often run in a loading-then-maintenance pattern: a higher loading dose over the first 46 weeks, then a lower maintenance dose

fatty acid oxidation (FAO) modulators (e.g., PPAR- agonists) can correct macrophage metabolic imbalance and promote M2 polarization (121, 122)

Brain Injury, 5 , 375-380